Know the boundary before you adopt it.
Setupidity is intentionally focused, and its documentation distinguishes what ships now from what may come later. It does not currently expose bundles, patches, per-user installation, services, environment variables, file associations, or arbitrary MSI table authoring.
Generated packages still need your Windows test matrix and your own Authenticode signing step. Cross-platform authoring removes a dedicated Windows build host; it does not remove Windows-specific release verification.